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The Göttingen Minipig

The microbiologically defined health status and the many similarities to humans make the Göttingen Minipig an ideal animal model in all types of biomedical studies.

The Göttingen Minipig was bred at the University of Göttingen, Germany, and is the result of crossbreeding the Minnesota minipig, the Vietnamese potbelly pig and the German Landrace pig. The Göttingen Minipig became available to Germany’s biomedical research community in the late 1960s. In 1992, the first colony of barrier-bred, microbiologically defined Göttingen Minipigs was derived at Ellegaard Göttingen Minipigs.

The Göttingen Minipig has a well-defined and strictly managed genetic background. In the beginning, the Göttingen Minipig was primarily used for dermal research but is now used in all fields of biomedical research, including basic research, toxicology, pharmacology and safety assessment of new medicines, medical devices, food additives and agrochemicals.

The Minipig’s skin, gastrointestinal tract, cardiovascular system, kidney and bladder are very similar to humans in terms of anatomy and function, lending themselves to pharmacological and toxicological investigations alike. The liver metabolism of Minipigs is similar to humans for most CYP isoenzymes.

Extensive background information is available. Contact us for further information.

The Göttingen Minipig is recognized by regulatory authorities, and the Rethink report has confirmed that the Minipig is a highly suitable non-rodent model for non-clinical safety testing.

Specific characteristics of the Göttingen Minipigs

CHARACTERISTIC COMMENT
Bred specifically for biomedical research Originally bred at the University of Göttingen to meet the demand from the German research community for a small pig for chronic studies
Well-defined, strictly managed genetics A Göttingen Minipig is essentially the same animal no matter from which of the three colonies it is acquired
Well-defined health status Health monitoring is performed two times a year
Available in large, uniform groups Background data is available
Comparability of organ systems in minipigs and humans Background data is available
Size / weight Possibility of imaging, surgery and dosing techniques that are not possible with all species

Quality and health status

As globally responsible for breeding and distribution of Göttingen Minipigs we see it as our main task to continuously ensure the good quality and high health status and to maintain and improve the animal welfare.

We respect the animals and recognize the fact that the health and animal welfare is of utmost importance in order to ensure that we also in the future can deliver high quality Göttingen Minipigs to the biomedical industry.

Due to the barrier facilities and lock systems the high health status is preserved and the minipigs are not exposed to any sources of infection.

The minipigs are health monitored twice a year and our facilities have been AAALAC accredited since 1998.

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