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Humanized IgG1/IgG4

This is a collection of available material about the Humanized IgG1/IgG4 Göttingen Minipigs. Here you will find articles, whitepapers, data, webinar recordings, links to recommended publications, and more.

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Whitepaper Hum GM v2025
Humanized IgG1/IgG4
Whitepaper: Humanized IgG1/IgG4 Göttingen Minipigs
Aug 13, 2025
A Translational Large Animal Model for Antibody-Based Therapeutics Göttingen Minipigs are particularly known for their small size, genetics and hea
Humaniseret IgG Göttingen Minipigs
Humanized IgG1/IgG4
Hematology, coagulation and clinical chemistry data on Humanized IgG Göttingen Minipigs
Sep 05, 2023
Therapeutic antibodies have become an important treatment modality in a variety of clinical disease areas such as cancer and autoimmune diseases. Howe
Behind the paper: Humanised Göttingen Minipigs – an alternative animal model to non-human primates in the preclinical safety assessment of therapeutic antibodies
Humanized IgG1/IgG4
Behind the paper: Humanised Göttingen Minipigs – an alternative animal model to non-human primates in the preclinical safety assessment of therapeutic antibodies
Jan 25, 2023
Recent years have seen tremendous advances in the treatment of human disease, largely due to the development of biopharmaceutical drugs. Among these,
Webinar recording
Humanized IgG1/IgG4
Webinar recording: Humanized Göttingen Minipigs for the toxicological testing of therapeutic antibodies
Oct 27, 2022
Abstract | The safety and efficacy of most novel biologicals is evaluated in animal models. However, most human therapeutic antibodies trigger xenogen