Juvenile

About the S11 guidelines The ICH guideline S11 focuses on nonclinical safety testing to support the development of paediatric pharmaceuticals. It w

The use of juvenile animals in preclinical toxicity studies conducted for drug development has generated substantial interest over the last decade (11

Göttingen Minipigs are a well-known non-rodent species used for developmental and juvenile toxicity studies (1, 2). To ensure research quality and ani

Introduction The Göttingen Minipig has now become widely accepted as a non-rodent species for safety testing, including juvenile safety testing due

Juvenile and neonatal studies Göttingen Minipigs provide a scientifically robust model for juvenile and neonatal studies, supporting the assessment

Drug therapy in paediatric patients is challenging in view of the maturation of organ systems and processes that affect pharmacokinetics (PK) and phar

Abstract | Juvenile animal studies are increasingly being used to support the development of paediatric medicines. Göttingen Minipigs are ideal in man