Genetically altered models
Humanized IgG Göttingen Minipigs
Ellegaard Göttingen Minipigs A/S November 3, 2022
Genetically altered Göttingen Minipigs, carrying a mini repertoire of human Ig-γ1/γ4 heavy and the human κ light chain genes, show tolerance to a broad range of human antibodies. This provides a novel model for safety testing and an important and viable alternative for toxicology studies of therapeutic antibodies in non-human primates.
Get full access to the entire science base
We provide free access to everyone interested in the papers and documents in the science base. Register once, and you can search our database unlimited.