Genetically altered models, Safety pharmacology
Rapid One-Step Generation of Genetically Modified Göttingen Minipigs for Human Disease Modelling
For decades Göttingen Minipigs has been used in biomedical research, with their many anatomical, physiological and pathophysiological similarities to humans, and as such play an important role as large animal models in translational studies. In recent years, the number of genetically altered Göttingen Minipigs has increased, as advanced genetic techniques simplify the generation of animals with precisely tailored modifications.
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