Genetically altered Göttingen Minipigs possess small modifications designed to replicate genetic alterations responsible for human disease.


Genetically Altered Göttingen Minipigs

In recent years, the number of genetically altered Göttingen Minipigs has increased, as advanced genetic techniques simplify the generation of animals with precisely tailored modifications.

These modifications are designed to replicate genetic alterations responsible for human disease. As such, genetically altered Göttingen Minipigs are valuable large animal disease models, and in addition, also considered promising donors for xenotransplantation.

Humanized Göttingen Minipigs

Humanized huIgG1/4 Göttingen Minipigs show tolerance to a broad range of human or humanized antibodies and provide a novel model for toxicological testing of therapeutic antibodies. 

The humanized huIgG1/4 Göttingen Minipigs, a genetically altered Göttingen Minipigs strain carrying a mini repertoire of human genes for the immunoglobulin heavy chains γ1 and γ4 and the immunoglobulin light chain κ, are now available at Ellegaard Göttingen Minipigs.

If you are interesting in this genetically altered minipig model, please contact Peter Vestbjerg, Head of International Sales: pve@minipigs.dk 


At Ellegaard Göttingen Minipigs we offer the opportunity to use Göttingen Minipigs as background strain for the creation of genetically altered minipigs based on:

  • a case-by-case assessment
  • approval of your specified project plan
  • a description of the specific sequence of the targeting construct

Furthermore, we offer contract breeding of genetically altered Göttingen Minipigs in our AAALAC accredited state-of-the-art Research Facility.

The Importance of Göttingen Minipigs in Biomedical Research

For decades Göttingen Minipigs have been used in biomedical research. With their many anatomical, physiological, and pathophysiological similarities to humans, they play an important role as a large animal model in translational studies.

Did you know...

Genetically altered Göttingen Minipigs models are highly relevant within:

  • Neurodegenerative diseases
  • Cardiovascular diseases
  • Eye diseases
  • Bone diseases
  • Cancers and epidermal skin diseases
  • Inherited metabolic diseases
  • Diabetes mellitus
  • Cystic fibrosis

Genetically altered Göttingen Minipigs

Download information about genetically altered Göttingen Minipigs for biomedical research.

Contact us

Please contact us if you are interested in further information about genetically altered Göttingen Minipigs.